Columbus Union Station, built in 1901 and designed by the Atlanta architectural firm of Bruce and Morgan, once served the Central of Georgia and the Southern. Passenger service ended in 1971. The building, also known as the Sixth Avenue Station, was listed on the National Register of Historic Places in 1980.
Rehabilitated as an office facility by Total System Services, Inc., Union Station now houses the Greater Columbus Georgia Chamber of Commerce. (1200 Sixth Avenue).
Below is an old postard of the station.
I found the information about the Depot and the vintage postcard on the the following web site: